Nanotechnology Colloquium
Colloquium Date: Monday, May 14, 2007

A bi-weekly event to present and discuss issues related to developments, applications and commercialization of nanotechnology.

Nanotechnologies in Biosafety Applications

Speaker: Jeremy Tzeng, PhD

Department of Biological Sciences Clemson University

(VIDEO CONFERENCED FROM THE AUSTIN OFFICE OF WINSTEAD PC)

Abstract: Many pathogenic microbes initiate diseases through carbohydrate-protein (adhesin-receptor) interactions. In this research, the antiadhesion and the pathogen detection capabilities of carbohydrate biofunctionalized nanomaterials (nanoparticles and nanotubes) were investigated. Polystyrene nanoparticles and carbon nanotubes with different carbohydrate biofunctional moieties (receptor molecules) were synthesized and evaluated for their ability to mediate agglutination of targeted E. coli strains. Carbohydrate microarrays were fabricated, and their applications in the identification/detection of pathogenic bacteria were evaluated. We have demonstrated that carbohydrate-biofunctionalized nanomaterials have great potential as agents for both antiadhesion therapy and pathogen detection. Titanium Dioxide (TiO2) photocatalysts exhibit strong oxidizing characteristic when illuminated with UV light. When illuminated, TiO2 photocatalysts could decompose organic compounds by oxidation. Research has shown that nanosized TiO2, particularly the anatase form, exhibits antibacterial properties. We examined the antibacterial properties of TiO2 nanoparticles in the brookite form. Modified TiO2 nanoparticles will be evaluated for their antimicrobial characteristics under visible light activation.

Bio:

Dr. Jeremy Tzeng
Dr. Tzeng received his undergraduate training at the Department of Food Science, Tunghai University, Taiwan. He completed his graduate training at the Department of Microbiology and Molecular Medicine, Clemson University, USA. Dr. Tzeng has taught microbiology courses at all levels. His research interests focus on the development of non-antibiotic approaches for the prevention and treatment of microbial infections. The overall goal of his research is to augment the efficacy and minimize the use of antibiotics. In one approach, he has developed bacterial adhesin-specific nanomaterials for physical purging of targeted pathogens. In a second approach, he is developing self-sterilizing surfaces for the removal of pathogens. The use of medicinal plant constituents for the treatment of multiple-drug-resistant (MDR) microbes and cancer cells is of great interest to Dr. Tzeng as the emergence of MDR microbes and cancer cells has hampered our current treatment approaches. To further minimize the emergence of drug-resistant microorganisms, a narrow spectrum antimicrobial peptide, Jenseniin P has been developed by Dr. Tzeng's research team for the treatment of acne. Dr. Tzeng is currently serving as the President of the SC Branch of the American Society for Microbiology. He is also serving on the USDA NC1031 Nanotechnology and Biosensor Committee. In this capacity, he is exploring the use of nanotechnologies to develop biosensors for the detections of food borne pathogens.


VENUE: You may attend the presentation from any one of these law offices of Winstead PC or from UT Dallas

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AUSTIN: Winstead PC
401 Congress Av., Ste 2100, Austin, TX 78701; 512-370-2800

DALLAS: The University of Texas at Dallas,
The School of Management,
800 West Campbell Road, Room SOM1.502 map
Richardson, TX 75080; 972-883-4568

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HOUSTON: Winstead PC
919 Milam, Ste 2400 Houston, TX 77002; 713-650-8400

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SAN ANTONIO: Winstead PC
700 N. St Mary St., Ste 1900 San Antonio, TX 78205; 210-277-6800

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THE WOODLANDS: Winstead PC
600 Town Center One, 1450 Lake Robbins Drive, The Woodlands, TX 77380; 281-681-5900


Program begins at 11:30am with a complimentary lunch provided by Winstead PC. Presentation begins at 12:00pm.

Event Coordinators:
Richard Fink 512-339-5020x130 dfink@appliednanotech.net
Max Roundhill 512-339-5020x120 roundhill@appliednanotech.net

Chairman: Dr. Zvi Yaniv

Registration deadline is Friday, May 11 at 5:00 PM Central.

To register, please send an email to Deepika Misra dmisra@winstead.com with your preferred attendance location.

   


Nanomaterials Applications Center
Walt Trybula, Ph.D.
Director
Texas State University
San Marcos, TX
(512) 245-6062


DVDs of selected presentations from previous speakers are available for a small fee (contact Max Roundhill mroundhill@appliednanotech.net)

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